Technology
Patents & Papers
Research outcomes and intellectual property behind our cardiac physiome technology.
Patents
| No. | Title | Application/Registration Date | Application/Registration Number |
|---|---|---|---|
| 1 | Heart simulation method and device based on gene mutation | [Application] Feb. 25, 2015. [Registration] May 24, 2017. | [Application] 10-2015-0026415 [Registration] 10-1741580 |
| 2 | Drug cardiotoxicity assessment method based on field potential signals of a multi-electrode array | [Application] Dec. 12, 2022. | [Application] 10-2022-0172632 |
| 3 | Method for evaluating drug cardiotoxicity using an ordered logistic regression model with multiple in silico biomarkers | [Application] Dec. 8, 2023 | [Application] 10-2023-0177231 |
| 4 | Stacking Ensemble Machine Learning Method for Predicting Drug TdP Risk Based on MEA Data | [Application] September 12, 2025 | [Application] 10-2025-0130412 |
Academic Journal Papers
| No. | Title | Date | Journal |
|---|---|---|---|
| 1 | Cardiosim-Tox: An Interpretable Multitask Deep Learning QSAR Platform with Multimodal Feature Fusion for Predicting hERG, Cav1.2, and Nav1.5 Blockade Risk and Potency | August 2026 | Archives of Toxicology |
| 2 | Improving Biomarker Robustness for in silico Cardiac Safety Assessment Through An Excitation-Contraction Coupling Model | June 2026 | Toxicology and Applied Pharmacology |
| 3 | Integrating Multi-Biomarker in silico Ventricular Cell Models with Ranking Algorithms for Enhanced Prediction of Drug-Induced Cardiac Risk | July 2026 | Computational Toxicology |
| 4 | Cardiovascular Digital Twin Personalization Using Arterial Blood Pressure-Driven Optimization of a Windkessel-Baroreflex Model | May 2026 | Biomedical Engineering Letters |
| 5 | Incorporating Inter-Individual Variability to Improve the Reliability of Predicted Outcomes in in silico Cardiac Safety Assessment | April 2026 | Toxicology and Applied Pharmacology |
Technology Transfer
| No. | Title | Receiving Institution | Year |
|---|---|---|---|
| 1 | Heart simulation method and device based on gene mutation | Kumoh National Institute of Technology Industry-Academic Cooperation Foundation | 2023.08.16. |
Certificates
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경북 구미 강소연구개발특구 Tech-Chanllenge 우수상
한국연구재단 EDISON 전산의학 전문센터 공로상
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