Electrophysiology

Simulate the electrical activity of excitable cells and tissues, from single neurons through to cardiac, smooth and skeletal muscle, and study ion channels, action potentials and arrhythmia mechanisms.

What's Inside

Sub-tools in this module

Neuron

Simulate action potential generation and propagation in neuronal models, exploring how ion channel dynamics shape firing patterns.

Ventricular Muscle

Run ventricular and atrial myocyte models to study ion channel currents, action potential morphology and drug-induced effects.

Smooth Muscle

Model the electrical activity of vascular and visceral smooth muscle cells and their role in tissue-level contraction.

Skeletal Muscle

Simulate excitation-contraction coupling in skeletal muscle fibers, from membrane depolarization to calcium release.

Atrial

Explore atrial myocyte electrophysiology, including remodeling processes associated with atrial fibrillation.

Use Cases

What you can do with this module

Study how ion channel mutations alter action potential shape and duration

Test the electrophysiological effect of a drug on cardiac, neuronal or muscle cells before in vivo work

Compare healthy vs. diseased cell models side-by-side

Generate APD and conduction velocity restitution curves for downstream tissue and organ models

Explore arrhythmia mechanisms at the cellular and tissue scale

Build teaching materials that visualize excitable-cell electrophysiology

CardioSim